Stimulant Laxatives and Opioid-Induced Constipation
نویسندگان
چکیده
منابع مشابه
Osmotic and stimulant laxatives for the management of childhood constipation.
BACKGROUND Constipation within childhood is an extremely common problem. Despite the widespread use of osmotic and stimulant laxatives by health professionals to manage constipation in children, there has been a long standing paucity of high quality evidence to support this practice. OBJECTIVES We set out to evaluate the efficacy and safety of osmotic and stimulant laxatives used to treat fun...
متن کاملLaxatives Do Not Improve Symptoms of Opioid-Induced Constipation: Results of a Patient Survey.
Introduction Laxatives are commonly used to treat opioid-induced constipation, the commonest and most bothersome complication of opioids. However, laxatives have a nonspecific action and do not target underlying mechanisms of opioid-induced constipation; their use is associated with abdominal symptoms that negatively impact quality of life. Objective To assess the effects of laxatives in pati...
متن کاملOpioid Induced Constipation
The definitions of constipation include a reference to infrequent, difficult or incomplete bowel evacuation that may lead to pain and discomfort; with stools that can range from small, hard ’rocks’, to a large bulky mass. Constipation may be debilitating among those who require chronic analgesia (7); OIC or OBD affected an average of 41 % patients taking an oral opioid for up to 8 weeks in a me...
متن کاملMethylnaltrexone or laxatives for the Management of Opioid-induced Constipation among Palliative Patients on Opioid Therapy: Evidence-based Review
Constipation is a common symptom in advanced cancer patients. Studies have demonstrated that 40 to 80% of patients on a palliative care service have constipation. This proportion increases to ≥ 90% when patients are treated with opioids [1-5]. Fredericks, Hollis and Stricker, [6-10] defines constipation as less than three defecations per week (or change from usual pattern), or the subjective sy...
متن کاملThe Clinical Challenge of Opioid-induced Constipation: Insights from the Opioid-induced Constipation Clinical Audit
Objective: Constipation is the most common and often most debilitating adverse effect associated with opioid use. Opioid-induced constipation persists for the duration of therapy. The aims of this clinical audit were to investigate the GP management of opioid-induced constipation, gain insights on how to improve its management and determine if the audit could improve the management of opioid-in...
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ژورنال
عنوان ژورنال: Journal of Pain and Symptom Management
سال: 2012
ISSN: 0885-3924
DOI: 10.1016/j.jpainsymman.2011.12.002